Cavo-Tricuspid Isthmus Block Durability After Pulsed Electric Field Ablation
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorInstitute for Clinical and Experimental Medicine
About this trial
This study seeks to assess the acute durability of the CTI block when PEF energy is used. Second goal is to establish the optimal waiting time for the conduction recovery after PEF CTI ablation and to assess the utility of routine adenosine testing for dormant conduction. Moreover, this study aims to investigate the differences in acute efficacy and adverse events (hemolysis, coronary vasospasm) between the two available configurations (basket or flower) of the pentaspline Farawave catheter (Farapulse-Boston Scientific Inc, USA).
Eligibility criteria
Qualifiers
patients with paroxysmal AF undergoing PVI by PEF energy with documented typical atrial flutter or patients with persistent AF in whom catheter ablation of CTI is planned as a part of a complex procedure
Age ≥ 18 years at the time of study enrollment
Signed informed consent
Disqualifiers
- LA diameter > 65 mm (measured in the parasternal long-axis view)
History of CTI ablation in the past
History of cardiac valve surgery
Significant valvular defect
Trial design
Treatments tested in this trial
- Catheter ablation of cavotricuspid isthmus using flower configuration of the Farapulse catheter
- Catheter ablation of cavotricuspid isthmus using basket configuration of the Farapulse catheter
Treatment groups
150 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov