CBT Enhanced With Social Cognitive Training vs. CBT Only With Depressed Youth

ConditionDepression
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age13-17
SponsorVanderbilt University

About this trial

Depression in youth is a serious public health concern for which more personalized treatments are needed. This randomized controlled trial will test the effect of an intervention aimed at enhancing social cognitive capacities (e.g., ability to take another's perspective), thereby making treatment of depression in youth more efficient and effective. Participants in the R33 (N=82) will be youth between ages 13- through 17-years-old currently experiencing depression. Youth will be randomized to either an enhanced CBT intervention that teaches social cognitive skills, particularly social perspective taking and theory of mind (CBTSCT) as compared to CBT only. The primary target is improvement in both social cognitive skills and depressive symptoms at post-treatment and at a 6-month follow-up.

Eligibility criteria

Qualifiers

Participants ages 13- through 17-years-old

Youth must have a diagnosis of a current depressive disorder (e.g., major depressive episode; persistent depressive disorder) or a score on the Patient Health Questionnaire (PHQ9) > 15

Disqualifiers

ever met criteria for a diagnosis of bipolar disorder, schizophrenia, autism, or conduct disorder

current alcohol or substance use disorder with significant impairment

imminent risk of suicide

reading level < 4th grade

Trial design

Treatments tested in this trial

  • Cognitive behavioral therapy plus social cognitive training (CBTSCT)

Treatment groups

82 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Vanderbilt University

Lead sponsor

National Institute of Mental Health (NIMH)

Collaborator