cDNA and Residual Disease After Chemoradiotherapy for Locally Advanced Head and Neck Squamous Cell Carcinomas

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorCentre Jean Perrin

About this trial

The goal of this ancillary clinical trial is to evaluated circulating DNA as a biomarker of residual disease after chemoradiotherapy for locally advanced head and neck squamous cell carninoma.

The main question it aims to answer is :

\- Does circulating DNA (cDNA) be able to detect residual disease 3 months after the end of chemoradiotherapy ? Researchers will compare detection of cDNA at 3-months and objective response (clinical and radiological).

Participants will :

* be included in the main study (Neck-TAR) * have a blood sample 1 and 3-month after the end of treatment

Eligibility criteria

Qualifiers

Patient included in NeckTAR study

Written informed consent signed for NeckTAR-IN study

Affiliation to the French social security system

Disqualifiers

None

Trial design

Treatments tested in this trial

  • blood sampling

Treatment groups

59 Participants
are divided into 1 treatment group

Sponsors and collaborators