Celiac Disease Genomic Environmental Microbiome and Metabolomic Study
ConditionCeliac Disease
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeUp to 6
SponsorMassachusetts General Hospital
About this trial
Celiac disease (CD) is a complex disease caused by eating gluten, a protein contained in wheat, rye, and barley. It is well known that many factors contribute to the development of CD, including the genes that you have and the foods that you eat. In the CDGEMM study, we will consider as many of these factors as possible and study how they each contribute to disease development. If the investigators find that any one factor, or combination of factors, increases the risk of developing CD, we will be able to apply this information and help prevent or detect disease in high-risk children in the future.
Eligibility criteria
Qualifiers
Newborns and infants less than 6 months of age who have not been introduced to solid foods (exclusive breast milk or formula diet)
First-degree relatives of patients affected with biopsy-proven CD
Disqualifiers
Infants older than 6 months of age
Inability or unwillingness of legal guardian/representative to give written informed consent
Trial design
Treatments tested in this trial
- Not listed
Trial groups
500 Participants
are grouped into 1 trial groupSponsors and collaborators
Massachusetts General Hospital
Lead sponsor
University of Roma La Sapienza
Collaborator
Università Politecnica delle Marche
Collaborator
Source ClinicalTrials.gov