Central Sensitization in Painful and Painless Diabetic Peripheral Neuropathy
ConditionDiabetes Mellitus (DM)
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorInonu University
About this trial
This research is structured as a cross-sectional observational study. The primary objective is to compare central sensitization across painful and painless phenotypes of diabetic peripheral neuropathy. The study will be conducted among individuals diagnosed with type 2 diabetes mellitus at the Department of Geriatrics, İnönü University Turgut Özal Medical Center. All assessments will be administered in accordance with a rigorously standardized protocol.
Eligible participants will include individuals aged 18 to 80 years who have had a confirmed diagnosis of type 2 diabetes mellitus for at least one year, are capable of comprehending and following verbal instructions in Turkish required for the study procedures, and provide written informed consent.
All statistical analyses will be performed using IBM SPSS Statistics (v.29, Armonk, NY, USA) and JASP (v.0.18, Amsterdam, Netherlands).
Eligibility criteria
Qualifiers
Being between 18 and 80 years of age
Having a diagnosis of Type 2 diabetes mellitus for at least 1 year
Providing written informed consent to participate in the study
Disqualifiers
Non-diabetic causes of polyneuropathy (alcohol, chemotherapy, vitamin deficiencies, renal failure, hypothyroidism, etc.)
Active ulcer, infection, or severe vascular insufficiency in the lower extremity
Central nervous system disorders (stroke, multiple sclerosis, spinal cord injury, etc.)
Skin lesions, dermatitis, wounds, or infection in the test areas (foot or forearm)
Trial design
Treatments tested in this trial
- Not listed
Trial groups
128 Participants
are grouped into 4 trial groupsSponsors and collaborators
Source ClinicalTrials.gov