Cerclage With Progesterone Versus Progesterone Only in Singleton Pregnancies
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18+
SponsorMỹ Đức Hospital
About this trial
This study compares the effectiveness of cervical cerclage with vaginal progesterone to vaginal progesterone only for the prevention of preterm birth in women with a singleton pregnancy and a short cervical length. Participants will be randomly assigned in a 1:1 ratio to receive cerclage plus progesterone or progesterone only.
Eligibility criteria
Qualifiers
Maternal age ≥18 years
Singleton pregnancy
Cervical length ≤ 25 mm, measured by TVS at the second-trimester ultrasonography (16 0/7 - 24 0/7 weeks of gestation)
Not participating in any other study which has intervention on maternity or fetus
Disqualifiers
Cervical dilation with visible amniotic membranes or amniotic membranes prolapsed into the vagina
Major congenital abnormalities of the fetus
Intrauterine fetal demise
Presence of severe vaginal discharge*
Trial design
Treatments tested in this trial
- Cervical cerclage
- Vaginal progesterone
Treatment groups
328 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov