About this trial
The CERSTIM study is a physiopatholgical study investigating transcranial alternating current stimulation in stroke patients in the cerebello-motor loop.
The design is a cross over design testing two frequencies in the gamma band and one placebo.
We will use behavioural data, functional MRI, and Electroencephalography to disentangle the effect of tACS and its frequency.
Healthy participants will be also recruited.
Eligibility criteria
Qualifiers
Male or female aged 18 years or older on the day of inclusion.
Affiliated with a social security system, Universal Health Coverage (CMU), or any equivalent scheme.
Ischemic stroke or intraparenchymal hematoma that occurred more than 6 months ago, with no upper time limit.
Motor deficit of the upper limb confirmed by the ARAT scale, with the ability to grip and press on a tablet.
Disqualifiers
Total paralysis of the affected hand
Conditions that are life-threatening or could compromise follow-up during the study period
Contraindications to MRI and tACS (ferromagnetic surgical clips, ocular implants, intraocular or nervous system metallic foreign bodies, implants or metallic objects likely to concentrate the radiofrequency field, cochlear implants, brain or cardiac stimulators, presence of a craniotomy scar)
Participation in another biomedical study focused on motor or overall recovery during the same period, or current exclusion period from another biomedical study
Trial design
Treatments tested in this trial
- tACS Transcranial alternating stimulation