Cerebral and Cognitive Markers of Treatment Resistance in Obsessive Compulsive Disorder

ConditionOCD
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-70
SponsorCentre Hospitalier Henri Laborit

About this trial

This study aims to define individual profiles of treatment resistants in order to find indicators and predictors of the therapeutic response.

Eligibility criteria

Qualifiers

Obsessive compulsive disorder diagnosed according to Diagnostic and Statistical Manual 5 criteria (patients will be included regardless of the severity and resistance of their pathology and their levels of executive functions)

Understand and accept the constraints of the study

Be a beneficiary or affiliated to a Health Insurance scheme

Disqualifiers

Present one of the diagnoses according to the criteria of the DSM 5: schizophrenic disorders, substance abuse or dependence to a substance according to the criteria of the M.I.N.I. version 5.0 (Sheehan et al., 1998)

Generalized anxiety disorder, social anxiety, nicotine dependence and history of a major depressive episode are not exclusion criteria according to the M.I.N.I. version 5.0 (Sheehan et al., 1998)

Have a serious intercurrent pathology

Being a pregnant woman

Trial design

Treatments tested in this trial

  • Functional MRI

Treatment groups

100 Participants
are divided into 2 treatment groups