Cerebral Blood Flow in Term and Preterm Neonates Using Doppler Ultrasonography
ConditionCerebral Blood Flow
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age1-48
SponsorAssiut University
About this trial
This study aims to evaluate cerebral blood flow in stable term and preterm newborns using Doppler ultrasonography. By measuring and comparing PSV, EDV, RI, and PI in the main brain arteries, the study seeks to identify normal physiological differences in cerebral perfusion across different gestational ages. The main goal is to establish reference values that can guide clinical monitoring, allow early detection of blood flow problems, and improve neuroprotective care in newborns.
Eligibility criteria
Qualifiers
Term neonates ≥ 37 weeks of gestational age.
Preterm neonates < 37 weeks' gestational age.
Hemodynamically stable infants at the time of examination.
Parental/guardian informed consent obtained.
Disqualifiers
Infants aged more than 48 hours after birth.
Neonates with major congenital anomalies (cardiac, neurological, or craniofacial).
Suspected or confirmed intracranial hemorrhage or brain malformations, such as intraventricular hemorrhage, may influence RI measurements and interfere with accurate assessment of cerebral blood flow.
Neonates requiring inotropic support at the time of scan.
Trial design
Treatments tested in this trial
- Not listed
Trial groups
200 Participants
are grouped into 2 trial groupsSponsors and collaborators
Source ClinicalTrials.gov