for patients connected to VA ECMO due to cardiogenic shock, monitoring:
1. Cerebral Oximetry 2. ECMO Parameters ECMO blood flow (L/min) every 12 hours. Sweep gas flow Cannulation configuration 3. Pulmonary Artery Catheter Data and hemodynamics:
Cardiac output / cardiac index, SvO₂, Central venous pressure (CVP). 4. other variables: P/F ratio, MAP, Heart rate, Arterial blood gases, hemoglobin, Lactate, Vasopressor / inotrope doses and Sedation score (RASS). 5. Echocardiography parameters: recorded every 12 hours. LV ejection fraction. LVOT VTi. LVED dimension. Aortic valve opening. 6. Follow-up data:
* ECMO duration. * Need for oxygen therapy/mechanical ventilation. * ICU survival.
Age ≥ 18 years
Patients supported with veno-arterial ECMO.
Presence of a pulmonary artery catheter.
Expected ECMO support ≥ 24 hours.
Pre-existing severe neurological injury (e.g. massive stroke, traumatic brain injury).
Intracranial pathology affecting NIRS reliability.
Facial or scalp conditions preventing NIRS probe placement.
ECMO duration < 48 hours.
Assiut University
Lead sponsor
Cairo University/ECMO unit
Collaborator