Changes in Inhibition and Valuation After Eating
ConditionBulimia Nervosa
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-45
SponsorIcahn School of Medicine at Mount Sinai
About this trial
An impaired ability to exert control has been implicated in bulimia nervosa (BN), but this impairment may not represent a stable trait or be the most effective focus for treatment. This project aims to understand how predictions and value-based decisions about control may be abnormally influenced by eating in individuals with BN, thereby maintaining cycles of binge eating, purging, and restriction.
Eligibility criteria
Qualifiers
Female
Aged 18 to 45 years
Current BMI greater than or equal to 18.5kg/m2 but under 30kg/m2
Right-handed
Disqualifiers
Medical instability
Ongoing medical treatment, medical condition, or psychiatric disorder that may interfere with study variables or participation
Shift work
Pregnancy, planned pregnancy, or lactation during the study period
Trial design
Treatments tested in this trial
- Fasting state
- Fed state
- Magnetic Resonance Imaging
Treatment groups
150 Participants
are divided into 2 treatment groupsSponsors and collaborators
Icahn School of Medicine at Mount Sinai
Lead sponsor
National Institute of Mental Health (NIMH)
Collaborator
Source ClinicalTrials.gov