Changes in Neuroplasticity Following Intensive Rehabilitation of Aphasia and/or Apraxia of Speech

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorKarolinska Institutet

About this trial

The present study aims to investigate the short- and long-term effects of two weeks of intensive speech-language pathology intervention with additional physiotherapy, on aphasia and apraxia of speech (AOS) and their neural correlates in thirty persons with chronic stroke. Changes are studied following intensive treatment of aphasia and AOS with standardised speech-language testing and testing of communication and with voxel-based morphometry (VBM) analysis and resting state functional connectivity (rsFC).

Eligibility criteria

Qualifiers

Aphasia 7 months post stroke diagnosed by SLP

Apraxia of Speech 7 months post stroke diagnosed by SLP

Disqualifiers

Dementia

Severe loss of sight

Severe loss of hearing

Metal implants (preventing fMRI)

Trial design

Treatments tested in this trial

  • Multimodal Intensive Rehabilitation of Aphasia and Apraxia of Speech

Treatment groups

30 Participants
are divided into 1 treatment group

Sponsors and collaborators

Karolinska Institutet

Lead sponsor

University of Malaga

Collaborator