Characteristics of Hypophosphatasia in Adult Patients in Rheumatology and Their Value in Developing an Algorithm to HPP-diagnosis - the COHIR Multi-center Study

ConditionHypophosphatasia

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18+

SponsorUniversity of Bonn

About this trial

Non-interventional, prospective, multi-center investigation with exploratory data analysis to assess the proportion of patients with hypophosphatasia presenting at departments of rheumatology and to establish an algorithm to HPP diagnosis

Eligibility criteria

Qualifiers

Written informed consent

Age > 18 years

Clinical suspicion of hypophosphatasia

Evidence of an abnormal ALP (ALP below LLN) within the clinical routine screening

Disqualifiers

Failure to meet the inclusion criteria listed above

Trial design

Treatments tested in this trial

Second alkaline phosphatase measurement

Treatment groups

720 Participants

are divided into 2 treatment groups

Sponsors and collaborators

University of Bonn

Lead sponsor

Source ClinicalTrials.gov