Characterization of Circulating and Tumor-infiltrating Immune Cells in Malignant Brain Tumors
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorPietro Mortini, MD, Prof.
About this trial
The goal of this observational study is to characterize the circulating leukocyte profile and the immune T cells distribution within the tumor in patients with malignant brain tumors and to correlate these findings with the oncological outcome.
Participants will be subjected to blood sampling before surgery and for 12 months of follow-up. Additional sampling and analysis will be performed on tumor samples.
Eligibility criteria
Qualifiers
Adult patients (≥18 years)
Able to express informed consent
With primary or secondary malignant brain tumor
Requiring neurosurgical treatment (radiosurgery, stereotactic biopsy, surgery)
Disqualifiers
Patients who do not meet inclusion criteria.
Trial design
Treatments tested in this trial
- Circulating leukocytes immunophenotype
- Tumor sampling
Treatment groups
200 Participants
are divided into 1 treatment groupSponsors and collaborators
Pietro Mortini, MD, Prof.
Lead sponsor
IRCCS San Raffaele
Sponsor institution
Source ClinicalTrials.gov