Characterization of JAK1 and JAK2 Activation in Gingival Tissues During Homeostasis and Periodontitis

ConditionsPeriodontitis Periodontal Diseases Periodontal Inflammation Gingival Diseases Periodontal Attachment Loss

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18+

SponsorUniversity of Chile

About this trial

The goal of this observational study is to examine JAK1/2 pathway activation in gingival tissues from adults with healthy gingiva and those with inflamed gingiva (periodontitis). The main question it aims to answer is:

Is the JAK1/2 pathway overactivated in periodontitis compared to health?

Participants with healthy gingiva and periodontitis will donate gingival tissue to study the JAK1/2 pathway. All participants wil receive diagnosis and treatment of the gingival condition.

Eligibility criteria

Qualifiers

Adults

Sistemically healthy

Disqualifiers

Active Maliganancy

History of radiation to the head-neck region

Chemotherapy or radiation within the last 5 years

History of hepatitis B/C or HIV infection

Trial design

Treatments tested in this trial

Not listed

Trial groups

30 Participants

are grouped into 2 trial groups

Sponsors and collaborators

University of Chile

Lead sponsor

Source ClinicalTrials.gov