Characterization of Skin and Facial Fat Pad Thickness Changes Following Microneedling Radiofrequency With and Without Topical Poly-L-Lactic Acid for Facial Rejuvenation

ConditionSkin Texture
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorThe University of Texas Health Science Center, Houston

About this trial

The purpose of this study is to evaluate whether microneedling RF subcutaneous fat pad thickness in the temple, submental, and cheek regions, to determine whether the addition of topical PLLA after microneedling RF alters or preserves subcutaneous fat pad thickness and to assess patient satisfaction and perceived outcomes following microneedling RF ± PLLA treatment.

Eligibility criteria

Qualifiers

Seeking facial rejuvenation for cosmetic concerns

Able and willing to provide informed consent

Willing to comply with study procedures and follow-up visits

Disqualifiers

Prior filler injection or energy-based device treatment to the face within the past 6 months

Previous facial surgeries

Pregnant or breastfeeding

Active infection, dermatitis, or open lesions in the treatment area

Trial design

Treatments tested in this trial

  • microneedling RF treatment
  • PLLA
  • Sterile Water as control

Treatment groups

30 Participants
are divided into 4 treatment groups