Characterization of T-cell Repertoire in Patients With Acute Myeloid Leukemia Undergoing Donor Stem Cell Transplant

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Southern California

About this trial

This research trial studies characterization of T-cell repertoire through next-generation sequencing in patients with acute myeloid leukemia undergoing stem cell transplant. Characterizing T-cell repertoire may help to understand if immune system plays a significant role in high risk patients with acute myeloid leukemia.

Eligibility criteria

Qualifiers

Diagnosis of AML scheduled to undergo HSCT at University of Southern California (USC)

Disqualifiers

Inability to provide consent because of severe mental disorders

Donor unwilling to provide consent

Trial design

Treatments tested in this trial

  • Biospecimen Collection
  • Laboratory Biomarker Analysis

Treatment groups

250 Participants
are divided into 1 treatment group

Sponsors and collaborators

University of Southern California

Lead sponsor

National Cancer Institute (NCI)

Collaborator