Chemoradiotherapy Sequenced Radical Surgery for Colorectal Cancer With PALNM
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorQilu Hospital of Shandong University
About this trial
In left-sided colon and rectal cancer, the occurrence of synchronous para-aortic lymph node metastasis is rare, with the incidence of being approximate 1-2%. Currently, there has been no standard treatment strategy for this situation. The present trial is designed to evaluate the safety and efficacy of para-aortic lymph node dissection for left-sided colon and rectal cancer with synchronous para-aortic lymph node metastasis
Eligibility criteria
Qualifiers
age at enrollment is ≥ 18 and ≤ 75 years
ECOG PS 0-1
histologically confirmed left-sided colon and rectal carcinoma
synchronous para-aortic lymph node metastases confirmed by PET-CT, and located below the level of renal veins and above the bifurcation of iliac artery
Disqualifiers
local invasion or distant metastasis other than para-aoritc lymph nodes
history of other malignant tumor
coupled with severe systematic diseases (recent myocardial infarction, cardiomyopathy, or acute pulmonary infection)
emergency surgery
Trial design
Treatments tested in this trial
- Radical surgery with PALND
- Radical surgery without PALND
Treatment groups
40 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov