China National Study of Adrenal Venous Sampling
ConditionHyperaldosteronism
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-65
SponsorChinese Academy of Medical Sciences, Fuwai Hospital
About this trial
This multicenter study intends to combine retrospective analysis and prospective registry to evaluate the success rate and safety of adrenal venous sampling (AVS) via antecubital and femoral approach for patients with primary aldosteronism. The consistency of AVS with pathological results and clinical outcomes, the factors affecting the success of AVS, and the optimal population for AVS will be aslo analyzed in this study.
Eligibility criteria
Qualifiers
Aged from 18 to 65 with no limits in sex;
Patients with confirmed primary aldosteronism;
Patients or their legal representatives sign written informed consent approved by the ethics committee；
Disqualifiers
Severe comorbidity, including stroke, myocardial infarction, heart failure, severe valvular heart disease, liver cirrhosis, and metastatic tumor within the previous 3 months；
An estimated glomerular filtration rate <45 ml/min/1.73 m2, or serum creatinine >176 μmol/L；
Patients who refuse adrenalectomy;
Suspected of having an adrenocortical carcinoma;
Trial design
Treatments tested in this trial
- adrenal venous sampling
Treatment groups
1,500 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov