Circuit-Based Approach to Suicide: Biomarkers, Predictors, and Novel Therapeutics

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorMassachusetts General Hospital

About this trial

This neuroimaging study is a clinical trial investigating the effectiveness of intermittent theta-burst transcranial magnetic stimulation (iTBS-TMS) to the inferior parietal lobule (IPL) in reducing suicide risk in patients with major depressive episode (MDE) or borderline personality disorder (BPD).

Eligibility criteria

Qualifiers

18-65 years of age

Diagnosed with BPD or MDE

Chief complaint of suicidal thoughts and behaviors

Disqualifiers

Neurological conditions with known structural brain lesion

Prior neurosurgical procedure

Metal in the body that is ferromagnetic or metal injury to the eyes

Epilepsy

Trial design

Treatments tested in this trial

  • Intermittent Theta Burst Transcranial Magnetic Stimulation (Active)
  • Intermittent Theta Burst Transcranial Magnetic Stimulation (Sham)

Treatment groups

80 Participants
are divided into 4 treatment groups

Sponsors and collaborators