Circulating circRNA in Acute Ischemic Stroke

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorThe Affiliated Hospital of Xuzhou Medical University

About this trial

CRAST is to analyze the expression pattern of circular RNA (circRNA) by bioinformatics analysis in patients with acute ischemic stroke and healthy control. The candidate circRNA will be verified as biomarkers for the detection and prognosis of acute ischemic stroke.

Eligibility criteria

Qualifiers

Aged 18 years or older

Confirmed acute ischemic stroke by a diffusion-weighted imaging-position lesion on magnetic resonance imaging (MRI) and a new lesion on a brain computed tomography (CT) scan

Within 72 hours of symptom onset

Good performance status

Disqualifiers

a history of hemorrhagic infarction, chronic kidney/liver diseases, peripheral arterial occlusive disease, active malignant disease, and inflammatory or infectious diseases

Trial design

Treatments tested in this trial

  • Quantitative Real-time polymerase chain reaction

Treatment groups

500 Participants
are divided into 2 treatment groups