Circulating Tumor DNA in Patients Summoned for Colonoscopy; - a Liquid Biopsy for Detection, Characterization, Individualized Treatment and Follow-up of Colorectal Cancer

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorHelse Nord-Trøndelag HF

About this trial

CoLiQ is a clinical study designed to evaluate the clinical usefulness of circulating tumor DNA (ctDNA) markers found in blood, as a liquid biopsy for diagnosis, prognosis and follow-up of colorectal cancer. The main questions it aims to answer are: 1) Can a panel of ctDNA markers identify CRC patients among the other patients summoned for colonoscopy? and 2) Does the type, number and level of ctDNA markers vary with the subtype and clinical course of CRC? Participants will be asked to answer a questionnaire and give a blood sample at inclusion. In addition, patients with CRC will be asked to give an extra test tube at their routine treatment and follow-up blood sampling.

Eligibility criteria

Qualifiers

Patient ≥ 18 years old summoned for colonoscopy

Patient able to understand and sign written informed consent

Disqualifiers

Patient < 18 years old

Patient unable to understand or give written informed consent

Patient unlikely to comply with the protocol (e.g. uncooperative attitude, inability to return for subsequent visits) and/or otherwise considered by the investigator as unlikely to complete the study

Trial design

Treatments tested in this trial

  • liquid biopsy

Treatment groups

No treatment groups listed

Sponsors and collaborators

Helse Nord-Trøndelag HF

Lead sponsor

Norwegian University of Science and Technology

Collaborator