Clinical and Functional Outcomes After ACL Reconstruction Versus Primary Repair

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-40
SponsorGazi University

About this trial

The anterior cruciate ligament (ACL) is the primary structure responsible for controlling anterior-posterior translation and rotational stability of the knee joint. Although ACL reconstruction has long been considered the gold standard among surgical interventions following ACL injury, arthroscopic primary repair techniques have recently regained interest. With advances in minimally invasive surgical procedures, refined patient selection criteria, and improved rehabilitation strategies, the clinical effectiveness of primary repair is once again being re-evaluated. However, there remains a limited body of literature directly comparing the medium- to long-term effects of these two surgical techniques on neuromuscular performance, fatigue tolerance, and functional outcomes.

The aim of this study is to comparatively investigate postoperative muscle strength and endurance, isokinetic fatigue response, muscle oxygenation, proprioception, knee stability, postural control, and patient-reported outcome measures in individuals who have undergone ACL reconstruction or primary repair. Assessments will include low- and high-velocity tests performed on the Cybex Norm isokinetic dynamometer, a 33-repetition fatigue protocol at 300°/s, muscle oxygenation analysis using Train.Red NIRS, knee laxity measurement via the GNRB arthrometer, single-leg balance and landing evaluations using the KFORCE force platform, and subjective outcome measures (IKDC, ACL-RSI).

The findings of this study are expected to provide a more comprehensive understanding of how surgical technique influences physiological, biomechanical, and functional outcomes. This knowledge may contribute to the development of individualized rehabilitation approaches and evidence-based return-to-sport criteria.

Eligibility criteria

Qualifiers

Age 18-40 years

History of complete ACL rupture treated with ACL reconstruction

Surgery performed at Gazi University Department of Orthopedics and Traumatology

At least 12 months postoperative at the time of evaluation

Disqualifiers

Previous surgery for partial or chronic ACL tear

Concomitant multi-ligament knee injuries

Prior surgery on the ipsilateral or contralateral knee

Lower extremity malalignment (e.g., significant varus/valgus)

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

45 Participants
are grouped into 3 trial groups

Sponsors and collaborators