Clinical Applicantion of Multi-Tracer PET/MR Imaging in Neurological Disorders/Disease

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-60
SponsorXuanwu Hospital, Beijing

About this trial

The goal of this clinical trial is to learn about the application of domestic PET/MR in major brain diseases. The main questions it aims to answer are:

* Overcome the bottleneck of early accurate diagnosis and treatment in major brain diseases clinical practice. * Promote the clinical application of domestic PET/MR, enhance international competitiveness. Participants will have a PET/MR scan of the brain.

Eligibility criteria

Qualifiers

Patients diagnosed with mild cognitive impairment (MCI) or Alzheimer's disease (AD), rapid eye movement sleep behavior disorder (RBD) or Parkinson's disease (PD), epilepsy, malignant brain tumors based on clinical guidelines.

Patients admitted to our hospital for inpatient treatment.

Disqualifiers

Patients who have undergone non-invasive/minimally invasive treatments such as radiotherapy or chemotherapy within the past three weeks. And Patients who have taken Alzheimer's disease-related and Parkinson's disease-related treatment drugs within the past month.

Patients with persistent seizures or status epilepticus that cannot be controlled by medication, resulting in an inability to cooperate with the examination.

patients with poorly controlled blood sugar and ineffective medication intervention.

Patients with absolute contraindications for PET/MR examination.

Trial design

Treatments tested in this trial

  • PET/MR

Treatment groups

2,300 Participants
are divided into 4 treatment groups

Sponsors and collaborators

Xuanwu Hospital, Beijing

Lead sponsor

Peking University Cancer Hospital & Institute

Collaborator

Shanghai Zhongshan Hospital

Collaborator

Wuhan TongJi Hospital

Collaborator

Henan Provincial People's Hospital

Collaborator

Sun Yat-sen University

Collaborator

Shanghai East Hospital of Tongji University

Collaborator

The First Affiliated Hospital with Nanjing Medical University

Collaborator

Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences

Collaborator

Shanghai Jiao Tong University School of Medicine

Collaborator