Clinical Application of Serum Anti-Müllerian Hormone (AMH) Measurements

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age10-44
SponsorChinese University of Hong Kong

About this trial

This study aims to assess the association of Anti-Müllerian hormone (AMH) with polycystic ovarian syndrome, premature ovarian insufficiency and fertility. The main objectives include the following:

1. To study the level of serum AMH in women with PCOS and to evaluate the utility of serum AMH in the diagnosis of PCOS. 2. To evaluate the level of serum AMH in women with POI and to evaluate the utility of serum AMH in the management of POI. 3. To evaluate the associations of basal AMH level with FSH level and AFC respectively for women undergoing ART treatment. 4. To determine the optimal regimen of gonadotropin for ovarian stimulation for women undergoing ART treatment. 5. To evaluate the predictive value of serum AMH in reproductive outcomes including oocyte quality, embryo quality, pregnancy loss, clinical pregnancy and live birth rate in women undergoing ART treatment.

Eligibility criteria

Qualifiers

Women attending the Paediatric and Adolescent Gynaecological Clinic and Gynaecological Endocrine Clinic of in the Department of Obstetrics and Gynaecology at the Prince of Wales Hospital for the management of PCOS and POI

Women attending the Assisted Reproductive Technology (ART) Unit of The Chinese University of Hong Kong for ART treatment

Disqualifiers

Women with age <10 or ≥45

Current or past diseases affecting gonadotropin, sex steroid secretion, clearance and excretion

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed