Clinical Characteristics of Small Intestinal Bacterial Overgrowth in Individuals with Abdominal Distention

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-60
SponsorShandong University

About this trial

Abdominal distention represents a prevalent clinical manifestation characterized by an unclear etiology and pathogenesis. This symptomatology is frequently observed in various conditions, including small intestinal bacterial overgrowth (SIBO) and abnormal orocecal transit time (OCTT). The utilization of the breath test as a non-invasive diagnostic approach has become widespread in recent years for identifying SIBO and abnormalities in OCTT. In this study, the prevalence of SIBO and OCTT irregularities in individuals presenting with abdominal distention was ascertained through the implementation of the breath test. Furthermore, the correlation between abdominal distention and SIBO/OCTT was analysed to enhance the elucidation of the underlying etiology of abdominal distention. These findings aim to offer valuable insights for refining clinical comprehension and strategies related to the diagnosis and treatment of abdominal distention.

Eligibility criteria

Qualifiers

Patients aged 18 to 70 years.

Patients presenting with the primary complaint of abdominal bloating and/or abdominal distension, or those exhibiting abdominal distension with prominence over other symptoms.

Disqualifiers

Patients who are pregnant or lactating.

Patients have history of gastrointestinal malignancy or gastrointestinal surgery.

Patients manifesting food intolerance or presenting with a confirmed diagnosis or suspicion of lactose intolerance.

Patients with urinary system (chronic kidney disease, etc.), immune system (scleroderma, etc.), nervous system (Parkinson's disease, etc.), mental system (depression, etc.), or other diseases outside the digestive system.

Trial design

Treatments tested in this trial

  • Breath test

Treatment groups

No treatment groups listed

Sponsors and collaborators

Shandong University

Lead sponsor

Qilu Hospital of Shandong University (Qingdao)

Collaborator

Jinan Central Hospital

Collaborator

Zaozhuang Municipal Hospital

Collaborator

Weihai Municipal Hospital

Collaborator

Central Hospital of Zibo

Collaborator

Weifang People's Hospital

Collaborator

Dezhou Hospital Qilu Hospital of Shandong University

Collaborator

Binzhou Medical University

Collaborator

Qihe Xian Renmin Hospital

Collaborator