Clinical Decision-Making in FAIS

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-35
SponsorUniversitaire Ziekenhuizen KU Leuven

About this trial

Femoroacetabular impingement syndrome is increasingly recognized as a contributor to cartilage injury and early hip osteoarthritis. Both structured conservative care and arthroscopic surgery can improve pain and function, but a major unresolved clinical problem is deciding who should continue conservative care and who should escalate to surgery, and when. Evidence indicates that shorter symptom duration before surgery is associated with better long-term improvement, meaning delays may reduce the chance of achieving meaningful recovery. Current decision-making still depends largely on static imaging and passive clinical examination, which do not capture the dynamic, movement-related nature of the condition, while advanced three-dimensional imaging and laboratory motion analysis are not practical for routine clinical monitoring. This study aims to address this gap by developing and validating feasible, clinic-ready dynamic assessment methods and integrating weight-bearing pelvic and spinal alignment with three-dimensional hip modeling to support more objective, individualized, and timely treatment decisions.

Eligibility criteria

Qualifiers

Voluntary written informed consent of the participant or their legally authorized representative has been obtained prior to any screening procedures

Male or Female, Age 18-35 years inclusive.

First consultation at participating site with clinical diagnosis of FAIS by a hip orthopaedic surgeon, including positive impingement tests and reduced hip ROM in the transverse plane compatible with FAIS.

Radiographic cam and/or pincer morphology on standard imaging (e.g. α-angle >60°, lateral center-edge angle >40°, crossover sign) as per local protocol.

Disqualifiers

Previous surgery on the bilareral hip.

History of major hip trauma or pediatric hip disease (e.g. Slipped capital femoral epiphysis, Perthes disease).

Developmental dysplasia (lateral center-edge ≤20°) or other severe structural deformity incompatible with the standard FAIS pathway.

Radiographic signs of hip degeneration (Tönnis grade >2).

Trial design

Treatments tested in this trial

  • Functional lateral x-ray scans
  • Multi-echo Fast Field Echo (mFFE) MRI
  • Markerless 3D motion capture
  • Marker-based 3D motion capture (optional)

Treatment groups

60 Participants
are divided into 2 treatment groups