Clinical Effects of Ringers Lactate Versus Sterofundin/ Plasmalyte Solution in Patients With Sepsis

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorCMH Lahore Medical College and Institute of Dentistry

About this trial

The goal of this clinical trial is to compare the clinical effects of using Ringer's Lactate and Sterofundin/ Plasmalyte as maintenance fluids in adult patients who have undergone abdominal surgery and are septic.

The primary outcome will be the change in serum lactate levels. Secondary outcomes will include renal function parameters, qSOFA scores, and the incidence of postoperative complications within the first 72 hours following surgery.

Eligibility criteria

Qualifiers

Underwent Abdominal Surgery and postoperative length of stay is more than 24 hours

ASA 1 to 4

Diagnosis of sepsis (qSOFA score 2 or more)

Disqualifiers

Patients with Renal failure/hepatic failure/severe metabolic acidosis

Patients requiring renal replacement therapy prior to enrolment

Patients with suspected poisoning

Pregnant women

Trial design

Treatments tested in this trial

  • Ringer's Lactate Crystalloid Solutions
  • Sterofundin (Bolus of crystalloids)

Treatment groups

82 Participants
are divided into 2 treatment groups