Clinical Research Evaluating Smoking Cessation With E-Cigarettes and Nicotine Therapy
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21+
SponsorBrown University
About this trial
This project will investigate the effects of alternative nicotine products on smoking, weight gain, and related outcomes.
Eligibility criteria
Qualifiers
body mass index (BMI) ≥ 30 kg/m2 (i.e., obese)
smoked ≥ 5 cigarettes/day during the past year
21 or older (due to minimum legal age EC restrictions)
exhaled breath carbon monoxide (CO) level > 6 ppm at Baseline (BL) (to confirm self-reported smoking)
Disqualifiers
received smoking cessation treatment of any kind in the past 30 days (actively quitting smoking),
currently using EC or NRT more than 2 days/week (this may affect responses to study-supplied products)
hospitalized for mental illness in past 30 days
heart-related event (e.g., heart attack, severe angina) in past 30 days
Trial design
Treatments tested in this trial
- Electronic Cigarettes (EC)
- Nicotine replacement therapy (NRT)
Treatment groups
60 Participants
are divided into 3 treatment groupsSponsors and collaborators
Brown University
Lead sponsor
National Institute of General Medical Sciences (NIGMS)
Collaborator
Source ClinicalTrials.gov