About this trial
We previously developed a novel non-trans thoracic esophagectomy, the single-port inflatable mediastinoscopy combined with laparoscopy for the radical esophagectomy of esophageal cancer.This study is evaluating the feasibility and safety of radical resection of single-port inflatable mediastinal mirror synchronization with laparoscopic esophageal carcinoma, as well as the clinical value of the radical resection of single-port inflatable mediastinal mirror synchronization with laparoscopic esophageal carcinoma as a new minimally invasive operation for esophageal carcinoma.
Eligibility criteria
Qualifiers
18 years old ≤ age ≤ 75 years old, no gender limit;
Patients who are diagnosed as esophageal malignant tumor by cytology or histology, and agree to undergo surgical treatment;
The preoperative clinical tumor staging is T1-2N0-1M0 patients; or T3N1-2M0 patients undergo neoadjuvant treatment (neoadjuvant chemotherapy, neoadjuvant chemoradiation, neoadjuvant radiotherapy, neoadjuvant chemotherapy and immunotherapy, neoadjuvant radiotherapy and immunotherapy After treatment), assess the tumor to achieve partial response (PR) and surgical resection is feasible;
The tumor is located in the thoracic esophagus;
Disqualifiers
People who suffer from other malignant tumors at the same time;
Patients with a history of esophagus or gastrectomy;
Patients with a history of mediastinal surgery or extensive abdominal cavity adhesion;
Patients with basic diseases such as cardiovascular and cerebrovascular diseases;
Trial design
Treatments tested in this trial
- Single-Port Inflatable Mediastinoscopy Combined With Laparoscopic-Assisted Small Incision Surgery
- Thoracoscopy Combined With Laparoscopic Surgery
Treatment groups
Sponsors and collaborators
Fifth Affiliated Hospital, Sun Yat-Sen University
Lead sponsor
General Hospital of Ningxia Medical University
Collaborator
Beijing Chao Yang Hospital
Collaborator
West China Hospital
Collaborator
Shanghai Chest Hospital
Collaborator
Peking University Cancer Hospital & Institute
Collaborator
The First Affiliated Hospital of Nanchang University
Collaborator
Changzhi Medical College
Collaborator
Zhangzhou Affiliated Hospital of Fujian Medical University
Collaborator
Harbin Medical University
Collaborator
Hubei Cancer Hospital
Collaborator
Jining First People's Hospital
Collaborator
Jiangsu Cancer Institute & Hospital
Collaborator
Nanfang Hospital, Southern Medical University
Collaborator