Clinical Study on the Risk of Left Atrial POP Ablation and Esophageal Injury Under Ultra-High Power and Related Influencing Parameters

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-85
SponsorThe Third People's Hospital of Chengdu

About this trial

This study aims to evaluate the risks of steam pop (POP) and esophageal injury, as well as related influencing parameters, under ultra-high power ablation technology. In the treatment of arrhythmias such as atrial fibrillation, cardiac ablation surgery is a common method. The use of ultra-high power ablation technology can shorten the operation time and improve effectiveness, but it may also increase the risk of damage to surrounding structures such as the esophagus. We will recruit a certain number of patients who are scheduled to undergo ultra-high power ablation surgery. We will record various parameters during the surgery, such as energy, time, and contact force, and monitor patients for signs of esophageal injury after the surgery. We expect that through this study, we can better understand the potential risks of ultra-high power ablation to the esophagus and identify the key parameters affecting these risks. This will help to improve surgical techniques, reduce complications, and enhance patient safety and surgical outcomes.

Eligibility criteria

Qualifiers

Patients aged between 18 and 80 years old.

Diagnosed with drug-refractory, symptomatic, paroxysmal atrial fibrillation.

Non-valvular atrial fibrillation.

Able to understand the purpose of the study, voluntarily participate in this research, and the patient or their legal representative signs the informed consent form, willing to complete follow-ups as required by the protocol.

Disqualifiers

Atrial fibrillation secondary to thyroid disease or other reversible factors;

Imaging studies indicating intracardiac thrombus;

Moderate to severe mitral stenosis or regurgitation;

Left ventricular ejection fraction <40%, or New York Heart Association (NYHA) functional class III or IV;

Trial design

Treatments tested in this trial

  • The ultra-high-power ablation group
  • The high-power ablation group

Treatment groups

120 Participants
are divided into 2 treatment groups

Locations

This trial has no locations