Surgical site infections (SSI) are a frequent complication in abdominal surgery. SSI lead to worse outcomes for the affected patients and significantly higher healthcare costs. Closed incision negative pressure wound therapy (ciNPWT) consists of a non-invasive, vacuum-assisted system that applies negative pressure to closed surgical incisions. It is currently unclear, if ciNPWT reduces SSI in patients undergoing abdominal surgery. This trial will investigate the effect of ciNPWT on SSI in abdominal surgery.
Elective or emergency laparotomy, or laparoscopy converted to laparotomy, including surgery for complications after elective operations
Incision length ≥ 10 cm
Centers for Disease Control and Prevention (CDC) wound class 1 and 2 (clean, clean-contaminated)
Abdominal closure with or without mesh implantation
Age ≤ 18 years
CDC wound class 4 (dirty/infected wound)
Organ transplantation
Sensitivity or allergy to silver
Insel Gruppe AG, University Hospital Bern
Lead sponsor
Clinical Trials Unit University of Bern
Collaborator