CoGENES Randomized Controlled Trial (RCT)

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Southern California

About this trial

This clinical trial evaluates the effectiveness of trained community engagement specialists for improving communication on colorectal cancer (CRC) prevention and genetic testing among Hispanic/Latino/a/x (H/L) communities. CRC is the second and third leading cause of cancer deaths among United States (US) H/L men and women respectively. Knowledge of inherited germline mutations (changes in a gene that occurs in a sperm or egg cell) is critical for understanding cause of disease and can impact patient treatment options and outcomes. Educational programs and participant engagement approaches focused on H/L individuals considering Latino cultural values, literacy, numeracy, barriers faced, cultural beliefs and attitudes, as well as language of participants are much needed to address these observed disparities. The Community Genetic Navigation Specialists (CoGENES) Program focuses on increasing knowledge, and preparing the CoGENES trainees to help respond to questions, fears, and concerns regarding genetic testing, counseling, biospecimen (sample of urine, blood, or tissue cells) donation and participation in clinical trials to H/L community members, patients and their families. CoGENES may improve communication on colorectal cancer prevention and genetic testing which can help reduce cancer disparities among H/L communities.

Eligibility criteria

Qualifiers

Must be 18 years of age or older

Ability to understand and the willingness to sign a written informed consent

Self-reported H/L ethnicity, of any race

Ability to read, write, and speak Spanish or English

Disqualifiers

Anyone younger than 18 years of age

Any person with major cognitive deficit or psychiatric impairment

Any person unable to read and write Spanish or English

Resides outside of Los Angeles County

Trial design

Treatments tested in this trial

  • Best Practice
  • Health Promotion and Education
  • Survey Administration

Treatment groups

140 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of Southern California

Lead sponsor

National Cancer Institute (NCI)

Collaborator