Cognitive and Immunologic Profiles of Patients With Olfactory Dysfunction After Smell Training
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorThe Cleveland Clinic
About this trial
A research study to assess the baseline olfactory function, mental health status, clinical severity, and immunological profile in patients with smell loss. The impact of a 3-month olfactory training program on smell function, immunological changes, and mental health in patients with smell loss will be evaluated.
The primary purpose of this study is to investigate tissue and blood samples to identify molecules that may be related to smell loss, ultimately aiming to develop future treatments for this condition and correlate with cognition.
Eligibility criteria
Qualifiers
Age less than 18 years-old
Present to rhinology clinic with CRS with nasal polyps
Sense of smell loss for any reason (other than trauma or tumor)
Disqualifiers
Patients < 18 years of age
Individuals with unilateral nasal polyps
Autoimmune diseases
Ciliary disorders
Trial design
Treatments tested in this trial
- Smell Training
Treatment groups
52 Participants
are divided into 4 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov