Cognitive-Frailty Gait Biomechanics for Early Dementia Detection
ConditionMild Cognitive Impairment (MCI)
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age50+
SponsorUniversiti Sains Malaysia
About this trial
The purpose of this study is to better understand how physical characteristics, walking patterns, and a blood-based brain health marker differ between older adults with dementia and healthy older adults.
Dementia is often associated with changes in physical health and movement, but these changes are not fully understood. This study asks whether people with dementia show differences in body composition, walking ability, and levels of brain-derived neurotrophic factor (BDNF), a protein involved in brain function, compared with individuals without dementia.
To answer this question, participants will complete a single assessment session that includes basic physical measurements, an assessment of walking while moving at a comfortable pace, and a small blood sample collection. The information collected will be used to compare the two groups and explore possible relationships between physical function, walking patterns, and BDNF levels.
Eligibility criteria
Qualifiers
Older adults aged 50 years and above
Able to ambulate independently without the use of walking aids
Must be able to understand instructions, communicate effectively
Free from any acute or unstable medical conditions at the time of assessment.
Disqualifiers
Present with any diagnosed neurological disorder such as stroke or Parkinson's disease
History of psychiatric illness, including major depressive disorder.
Individuals with uncontrolled cardiovascular, metabolic, or endocrine conditions
Have significant visual, auditory, or musculoskeletal impairments that may influence gait performance
Trial design
Treatments tested in this trial
- Not listed
Trial groups
60 Participants
are grouped into 2 trial groupsSponsors and collaborators
Source ClinicalTrials.gov