Cognitive-psychophysiological Treatment for Tics in Young People With Tourette's Syndrome With or Without Biofeedback

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age14-21
SponsorUniversité du Québec a Montréal

About this trial

The goal of this clinical trial is to compare the effectiveness of CoPs therapy with or without the therapeutic component of biofeedback in treating tics in Tourette Syndrome with emerging young adults.

Hypotheses:

1. The CoPs+Biofeedback treatment will improve the severity of tics (YGTSS) and the Clinical Global Impression, surpassing the clinical significance threshold of CoPs treatment alone. 2. We expect that the identified variables (psychosocial, neurocognitive, biological) will predict the improvement of tics.

Researchers will compare if the biofeedback treatment will improve the severity of tics.

* In the pre-test, participants will undergo two interviews, each lasting 3 hours. These interviews will assess (through a battery of tests) the severity of tics as well as the psychosocial, biological, and neurocognitive aspects of functioning. A general assessment of intelligence and executive functions will also be conducted. * They will next attend 10 to 12 therapy sessions, with or without biofeedback. (The biofeedback component is explained in more detail in the ''Study Design'' section). * The post-test follow-ups consist of two evaluations: one 3 months after the end of the treatment and the other 6 months after. The evaluation will be done using the same battery of tests as during the pre-test interview.

Eligibility criteria

Qualifiers

Have a diagnosis of TS or to experience bothersome tics;

Be aged 14 to 21 years inclusive at the start of therapy.

Disqualifiers

Present a sensorimotor impairment;

Have a diagnosis of intellectual disability (intelligence quotient below 75);

Alcohol or drug abuse;

A neurological issue (e.g., hemifacial spasms, Huntington's disease);

Trial design

Treatments tested in this trial

  • Cognitive psychophysiological
  • Cognitive psychophysiological and Biofeedback

Treatment groups

150 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Université du Québec a Montréal

Lead sponsor

Ciusss de L'Est de l'Île de Montréal

Collaborator