Previous work by the group convinced the researchers to pursue development of focused cognitive reappraisal training as a novel approach to treatment of BPD, either as stand-alone treatment or in concert with evidence-based treatments of BPD. The present proposal aims to refine and test a proposed clinical intervention for BPD patients, training in reappraisal-by-distancing, in terms of its ability to influence hypothesized neural and behavioral targets and, once that is established, to demonstrate its ability improve clinically relevant outcome measures.
Medically healthy men and women with Borderline Personality Disorder who are mentally competent and give informed voluntary written consent.
Participants will be between the ages of 18 and 55.
Within these requirements, the inclusion and
Participants with comorbid avoidant personality disorder will be included.
Participants who meet criteria for PTSD will be included as long as they are not actively experiencing symptoms.
Participants will not meet criteria for Schizotypal Personality Disorder.
Participants currently meeting criteria for Major Depressive Disorder will be excluded.
Icahn School of Medicine at Mount Sinai
Lead sponsor
William Marsh Rice University
Collaborator
National Institute of Mental Health (NIMH)
Collaborator