About this trial
Growing evidence indicates that many people who have chronic post-acute sequelae of SARS-CoV-2 infection (PASC) will experience ongoing neurological and musculoskeletal impairment that can affect gait and balance. Identifying the factors contributing to these impairments and how they influence functional mobility is the first step towards creating effective evaluation and treatment protocols. In this study the investigators will examine cognition, vision, proprioception, muscle strength, gait and balance in persons with and without PASC to understand how PASC may impact functional mobility through a cognitive-sensorimotor lens. Gait and balance will be studied in environments that stress cognitive and sensory abilities. Study outcomes will be critical for the development of evidence-based Veteran Health Administration diagnostic and standard-of-care protocols to address gait and balance dysfunction in Veterans with PASC for restoring their functional mobility and independence.
Eligibility criteria
Qualifiers
Older than 18 years of age
Positive PCR or Rapid COVID-19 test in the past
Onset of COVID-19 illness greater than 3 months prior to their participation in the study
Self-reported ability to walk 10 meters with or without external assistance prior to COVID-19 illness
Disqualifiers
Presence of severe cardiovascular and pulmonary disease and/or neurological and musculoskeletal disorders unrelated to COVID-19 (e.g., amputation, stroke, spinal cord injury)
Cognitive impairments precluding ability to provide informed consent.
Severe acute COVID-19 infection requiring hospitalization or diagnosed post-intensive care syndrome.
Presence of musculoskeletal, inflammatory, or neurological conditions mimicking Long COVID-19 symptoms (e.g., concussion within last 5 years, Chronic fibromyalgia, Myofascial pain syndrome, etc.)
Trial design
Treatments tested in this trial
- Not listed
Trial groups
Sponsors and collaborators
VA Office of Research and Development
Lead sponsor
Edward Hines Jr. VA Hospital
Collaborator