Cohort Study of Postoperative Cognitive Dysfunction After Off-Pump Coronary Artery Bypass Grafting
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorBeijing Anzhen Hospital
About this trial
This prospective cohort study aims to investigate postoperative cognitive dysfunction in patients undergoing off-pump coronary artery bypass grafting. Eligible patients will be enrolled before surgery and followed after surgery. Cognitive function will be assessed using the Montreal Cognitive Assessment before surgery and at predefined postoperative time points. Perioperative clinical information, including preoperative assessment data, intraoperative monitoring parameters, and postoperative clinical data, will be collected. The study will evaluate the occurrence of postoperative cognitive dysfunction and explore its association with perioperative factors.
Eligibility criteria
Qualifiers
Age 18 years or older
Scheduled to undergo elective off-pump coronary artery bypass grafting
American Society of Anesthesiologists physical status classification I to IV
Able to complete preoperative cognitive assessments, including the Mini-Mental State Examination and the Montreal Cognitive Assessment
Disqualifiers
Emergency surgery
Pre-existing diagnosed cognitive impairment or history of psychiatric disease
Preoperative cognitive impairment
Severe neurological disease, such as sequelae of stroke, that may interfere with cognitive assessment
Trial design
Treatments tested in this trial
- Off-Pump Coronary Artery Bypass Grafting
Treatment groups
600 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov