Cold Snare Versus Cold Forceps Polypectomy for Small Lesions

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorAzienda USL Modena

About this trial

The goal of this clinical trial is to compare the efficacy and the safety of a new device for cold forceps polypectomy (CFP)- a special jumbo forceps- to cold snare polypectomy (CSP) for small colorectal lesions, without adding peri- or post-procedural risks to the patient.

The main questions it aims to answer are:

* Does the cold forceps guarantee a complete endoscopic resection rate? * How many adverse events could the jumbo forceps reduce in comparison to CSP? * Does the lesion retrieval rate increase? * Does the polypectomy duration decrease? Participants will be randomized to one or to the other group when a polypoid or non-polypoid lesion is identified. If multiple polyps are found in the same patient, they will be removed using the same polypectomy technique.

If polypectomy cannot be performed using the indicated technique, a crossover will be done according to the best practice of care principles.

Eligibility criteria

Qualifiers

Patients aged ≥ 18 years;

Ability to provide informed consent;

Presence of at least one colorectal polypoid/non-polypoid lesion < 10 mm

Disqualifiers

Primary or secondary coagulopathy;

Improper interruption of dual antiplatelet therapy and/or antiplatelet therapy with P2Y12 receptor antagonists (clopidogrel, prasugrel, ticagrelor) and/or anticoagulant therapy;

Chronic inflammatory bowel diseases;

Inpatients undergoing colonoscopy;

Trial design

Treatments tested in this trial

  • Sampling from the resection margins

Treatment groups

312 Participants
are divided into 2 treatment groups

Sponsors and collaborators