Collection of Primary Human
ConditionNasal Disease
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-90
SponsorUniversity Hospital, Tours
About this trial
Treatment and prevention of respiratory infections are of great interest in many medical areas. Create a physical device covered by primary human nasal cells could be very usefull in order to analyse delivery and efficiency of drugs. In this context the aim of this project is to create a collection of primary cells from the human nasal epithelium.
This collection will be realised during programmed surgery, thanks to a specific device dedicated to collect nasal cells. Then the cells will be sent to the lab in order to grow at the air-liquid interface, which is an excellent 'ex vivo' model for their study.
Eligibility criteria
Qualifiers
Adult patients (age > 18 years) whose native language is French, or who understands French.
Affiliation with a French social security system (CMU accepted).
Informed consent, written and signed by the participant.
Planned rhinological surgery (meatotomy, septoplasty or turbinoplasty for example, but other surgeries as well)
Disqualifiers
Patients under court protection, guardianship or curatorship.
Pregnant or breast-feeding women (positive pregnancy test for women of childbearing age).
Patients presenting a major alteration of the mucosa or a malignant rhinosinus pathology.
Trial design
Treatments tested in this trial
- Collection of nasal cells during programme surgery
Treatment groups
100 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov