This is a multi-site comparative effectiveness randomized controlled trial (RCT) comparing annual fecal immunochemical testing (FIT) and colonoscopy for post-polypectomy surveillance among adults aged 65-82 with a history of colorectal polyps who are due for surveillance colonoscopy.
English or Spanish speaking
Personal history of colorectal polyps
Most recent colonoscopy with ≤2 non-advanced polyps
Currently due or coming due within 12 months for colonoscopy
Personal history of colorectal cancer
Personal history of genetic syndrome with high risk for colorectal cancer (e.g. Lynch Syndrome, Familial Adenomatous Polyposis Syndrome (FAP), or Serrated Polyposis Syndrome)
Personal history of inflammatory bowel disease (e.g. ulcerative colitis, Crohn's disease)
Most recent colonoscopy with advanced polyp(s) or ≥3 non-advanced polyps
Dartmouth-Hitchcock Medical Center
Lead sponsor
Patient-Centered Outcomes Research Institute
Collaborator