Colorectal Analysis for Signature Cancer Assessment Using Delta-HLD

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age45-75
SponsorEpiliquid Holding, Inc

About this trial

CASCADE (Colorectal Analysis for Signature Cancer Assessment Using delta-HLD Technology) is a proof-of-concept case-control study designed to evaluate the performance of delta-HLD, Epiliquid's proprietary liquid biopsy technology, for the detection of colorectal cancer. Epiliquid also integrates a proprietary bioinformatic system capable of identifying, ranking, and selecting tumor-specific methylation biomarkers for different cancer types. In this study, colorectal cancer-specific biomarkers will be evaluated in blood and tissue samples using delta-HLD technology, which enables sensitive and multiplexed detection through PCR. Study results will support the validation of Epiliquid's integrated platform as a minimally invasive and accessible diagnostic solution for colorectal cancer.

Eligibility criteria

Qualifiers

Candidate for colonoscopy or colorectal surgery

Willing and able to provide informed consent

Able to provide blood and/or tissue sample before treatment or resection

Disqualifiers

Prior history of colorectal cancer

Inflammatory bowel disease

Known hereditary cancer syndromes (e.g., Lynch, FAP)

Other active malignancies

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

600 Participants
are grouped into 2 trial groups

Sponsors and collaborators