Combined Distal Femoral Nerve Block for Pain Control After Knee Replacement
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorRamsay Générale de Santé
About this trial
The goal of this clinical trial is to see whether a combined distal femoral nerve block improves pain relief after total knee replacement in adults having planned surgery. The main questions it aims to answer are:
* Does the combined distal femoral nerve block reduce the amount of opioid needed in the post-anesthesia recovery room? * Does it preserve quadriceps muscle strength while improving postoperative pain control?
Researchers will compare the combined distal femoral nerve block to a saphenous nerve block alone to see if the combined block provides better analgesia without reducing leg strength.
Participants will:
* Receive either the combined distal femoral nerve block or the saphenous nerve block alone before surgery. * Also receive standard multimodal pain management, including anesthesia, surgical site infiltration, and postoperative pain medications. * Be assessed for pain, opioid use, nausea and vomiting, quadriceps strength, time to first standing, hospital stay length, and patient satisfaction from surgery until discharge.
Eligibility criteria
Qualifiers
Adult patients aged over 18 years.
Scheduled for total knee arthroplasty with multimodal analgesia.
Affiliated with or benefiting from a social security system.
Able to understand the study information and provide written informed consent.
Disqualifiers
Emergency surgery.
Weight under 50 kg.
Body mass index over 40 kg/m².
Contraindication to nefopam, non-steroidal anti-inflammatory drugs, local anesthetics, or morphine.
Trial design
Treatments tested in this trial
- Combined distal femoral nerve block
- Saphenous nerve block alone
- Standard perioperative care in both groups
Treatment groups
240 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov