Combined Effects of INF and OEP in Patients With Diabetic Peripheral Neuropathy

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50-75
SponsorRiphah International University

About this trial

DPN often leads to balance issues, sensory deficits, and chronic pain, which can severely impact daily functioning and independence. INF therapy aims to improve nerve blood flow and alleviate neuropathic symptoms through manual techniques, while the Otago Exercise Program focuses on enhancing strength and balance to reduce fall risk. By comparing these two interventions, this study seeks to identify effective strategies that can improve balance, reduce pain, and enhance the quality of life for individuals suffering from DPN

Eligibility criteria

Qualifiers

Age 50-75years

Both male and female patients will be included in the study

Patient with type 2 diabetes mellitus (diagnosed by the physician)

Patients with a score ≥ 4 on DN4 scale

Disqualifiers

Patient with presence of any other systemic disease rather than diabetes such as end-stage renal failure, uncontrolled hypertension, severe dyslipidemia, chronic liver disease, autoimmune disease, advanced chronic obstructive pulmonary disease etc

Patients with documented active alcohol or drug misuse

Patient with total or partial amputation of lower extremities

Participants will be also excluded if they were morbidly obese or if pregnant (self-reported)

Trial design

Treatments tested in this trial

  • Intraneural facilitation therapy
  • Otago exercise program
  • Intraneural facilitation therapy with Otago exercise program

Treatment groups

65 Participants
are divided into 3 treatment groups