Combined Exercise and Targeted Therapy for Post-Stroke Reading Deficits

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-85
SponsorKessler Foundation

About this trial

The goal of the proposed project is to test the effectiveness of a novel hybrid approach to treatment of reading disorders after stroke, in which exercise training will be used in combination with a targeted reading treatment. This approach is expected to increase cerebral circulation and help to rebuild and strengthen the damaged phonological neural networks. Through this combinatory approach, the study aims to enhance the reading and language improvements seen with existing treatments.

Eligibility criteria

Qualifiers

fluent and literate in English prior to stroke

1st ever stroke

more than 3 months post-stroke

post-stroke reading deficits, defined as reading aloud accuracy <83% for single words or <65% for readable nonwords

Disqualifiers

contraindication to MRI

prior neurological disease

developmental learning or reading disability (i.e., developmental dyslexia)

contraindication to exercise

Trial design

Treatments tested in this trial

  • Phono-Motor Therapy
  • Aerobic Exercise Training (AET)
  • Stretching

Treatment groups

70 Participants
are divided into 2 treatment groups

Sponsors and collaborators