About this trial
1. To evaluate the dynamic changes of lung ultrasound during electrical impedance tomography (EIT) PEEP titration and across the first week of ARDS. 2. To asses respiratory effort by diaphragmatic function, esophageal pressure, and EIT (Pendelluft phenomenon), and hyperinflammatory biomarkers, to predict P-SILI. 3. To develop predictive models for weaning success based on integrated EELI and thoracic ultrasound.
Eligibility criteria
Qualifiers
Adult >18 y/o.
Patient intubated and receiving mechanical ventilation > 24 hours.
Admitted into ICU, diagnosed as moderate or severe ARDS (ICD-10-CM: J80) according to Berlin definition.
Disqualifiers
Presence of Implanted Electronic Devices (pacemakers, implantable cardioverter-defibrillators).
Pregnancy.
No consent/inability to obtain consent and appropriate legal representative not available.
Trial design
Treatments tested in this trial
- Electrical impedance tomography