Comparation of Endoscopic Biopsy and Postoperative Specimen for the Molecular Diagnosis of Gastric Cancer
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-75
SponsorFudan University
About this trial
This study aims to test the hypothesis that the diagnosis for histological type, histological grade, LAUREN type, HER-2 expression, MSI/dMMR status, and EBV status in gastric cancer is at least as reliable when performed on endoscopic biopsy specimens as on surgical resection specimens.
Eligibility criteria
Qualifiers
Lower age limit of research subjects 18 years old and upper age limit of 75 years old.
Histologically proven primary gastric adenocarcinoma (Diagnostic biopsies must be collected within 12 months prior to enrollment).
Written informed consent from the patient.
Patients planned for radical R0 gastrectomy.
Disqualifiers
Female in pregnancy or lactation.
Patients with gastric cancer who can not undergo tumor resection
Suffering from other serious diseases, including cardiovascular, respiratory, kidney, or liver disease, complicated by poorly controlled hypertension, diabetes, mental disorders or diseases.
Patients with poor compliance or considered to be poor compliance.
Trial design
Treatments tested in this trial
- endoscopy
- Surgery
Treatment groups
510 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov