Comparative Efficacy of IV Parecoxib vs Lidocaine in Reducing Propofol Injection Pain
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorOman Medical Speciality Board
About this trial
Propofol is the most popular IV anaesthetic agent used for induction, however one of its known side effects is causing pain on injection, the gold standard method in preventing this pain is using lidocaine prior to injecting propofol. multiple drugs have been investigated to reduce the aforementioned pain, however there has been no study comparing lidocaine to parecoxib, an NSAID.
Eligibility criteria
Qualifiers
Adult patients, ≥18 years
ASA grading I-II
Patients undergoing elective surgical procedures across all surgical specialties.
Can speak Arabic or English
Disqualifiers
Difficulty in communicating.
Liver Cirrhosis patients
Renal failure or creatinine clearance (CrCl) ≤ 10umol/L,
Known Lidocaine, parecoxib and/or propofol allergy.
Trial design
Treatments tested in this trial
- Lidocaine, a local anaesthetic.
- Parecoxib 40mg
Treatment groups
30 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov