Comparative Evaluation of Melatonin Versus MTA on Vital Pulp Therapy in Young Permanent First Molars: An in Vivo Study
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age6-8
SponsorSuez Canal University
About this trial
The process of dental caries is dynamic and can be either reversible or irreversible depending on the balance between protective and pathologic factors in the oral cavity. Untreated dental caries causes pulpal injury, inflammation, and necrosis. Melatonin plays an essential role in the regulation of bone growth. The actions that melatonin exerts on odontoblasts may be similar to its action on osteoblasts.
Eligibility criteria
Qualifiers
No history of spontaneous pain, history of night pain or pain that not relieved by analgesics.
No pain on percussion.
No mobility.
Absence of abscess, purulent sinus or soft tissue edema.
Disqualifiers
Internal root resorption.
External root resorption.
Inter radicular or periapical bone destruction (radiolucency)
A deep carious lesion radiologically that approaches the pulp
Trial design
Treatments tested in this trial
- Mineral trioxide aggregate (dressing material)
- Melatonin (dressing material)
Treatment groups
45 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov